袁迎九 后建丽 丁文清
[摘要]意图 研讨与调查多囊卵巢综合征（PCOS）患者抗氧化及蛋白代谢的改变状况。办法 选取2016年10月～2017年6月在我院就诊的70例PCOS患者为调查组，挑选同期70名健康同龄妇女为对照组。检测两组研讨目标的抗氧化及代谢目标，并比较两组的检测成果，一起比较调查组不同严峻程度PCOS患者的检测成果，以Logistic回归剖析处理上述检测目标与PCOS的联系。成果 调查组的清蛋白代谢目标及MDA高于对照组，差异有统计学含义（P<0.05），其他血清抗氧化目标低于对照组（P<0.05），不同严峻程度PCOS患者的检测成果比较，差异有统计学含义（P<0.05），且Logistic回归剖析处理成果显现，上述检测目标与PCOS有亲近的联系（P<0.05）。定论 PCOS患者抗氧化及蛋白代谢目标显着不同健康同龄妇女，上述目标与PCOS有亲近的联系，可作为疾病诊断与医治的指导性目标。
[关键词]多囊卵巢综合征；抗氧化目标；蛋白代谢目标
[中图分类号] R711.6 [文献标识码] A [文章编号] 1674-4721（2017）12（b）-0162-03
[Abstract]Objective To study and observe the change status of antioxidation and protein metabolism of patients with polycystic ovary syndrome （PCOS）.Methods 70 patients with PCOS in our hospital from October 2016 to June 2017 were selected as the observation group，70 healthy women with the same age at the same time were selected as the control group.Then the antioxidation and protein metabolism indexes of two groups were detected，and the detection results of two groups were compared，the detection results of observation group with different severity degree of PCOS were compared too，and the relationship between those detection indexes and PCOS were analyzed by the Logistic regression analysis.Results The serum protein metabolism indexes and MDA of observation group were all higher than those of control group（P<0.05），other serum antioxidation indexes were lower than those of control group（P<0.05），the detection results of observation group with different severity degree of PCOS were compared，there were significant differences （P<0.05），and the results of Logistic regression analysis showed，those detection indexes all had close relationship to PCOS，the difference was statistically significant（P<0.05）.Conclusion The antioxidation and protein metabolism of patients with PCOS are obviously different to the results of healthy women with the same age，and those indexes all have close relationship to PCOS，and they can be as the guidance indexes of the disease.
[Key words]Polycystic ovary syndrome；Antioxidation indexes；Protein metabolism indexes
多囊卵巢综合征（PCOS）是育龄妇女的常见病，患者可体现出多毛、月经反常乃至不孕，而上述体现也是患者就诊的主要原因。临床关于PCOS的研讨多见[1-2]，而本病作为内分泌与代谢反常所造成的疾病，关于患者机体代谢方面的研讨则相对多见，而蛋白代谢方面的研讨虽可见，但研讨成果的差异较大。别的，抗氧化才能作为反响机体代谢的重要方面[3]，其在PCOS发作发展中的效果研讨也可见，但也存在研讨差异显着的状况。因而，本文对PCOS患者抗氧化及蛋白代谢的改变状况进行探求，现报导如下。
1材料与办法
1.1一般材料
选取2016年10月～2017年6月在我院就诊的70例PCOS患者为调查组，选取同期70例健康同龄妇女为对照组。对照组年纪21～38岁，均匀（29.9±6.7）岁；有生育史40例，无生育史30例。调查组年纪22～38岁，均匀（29.6±7.1）歲；有生育史38例，无生育史32例；病程7～50.5个月，均匀（26.3±5.7）个月；严峻程度：轻度20例，中度32例，重度18例。两组妇女的年纪与生育史等状况比较，差异无统计学含义（P>0.05），具有可比性。本研讨经我院医学伦理学委员会同意。endprint
